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Table 2 Melanoma top bio functions

From: Molecular changes induced by the curcumin analogue D6 in human melanoma cells

Bio-Function

p-value

N. of molecules

1 Cell death

3.34E-15 – 3.24E-02

194

2 Cellular function and maintenance

6.17E-14 – 3.24E-02

64

3 Cancer

1.22E-13 – 3.24E-02

306

4 Cell cycle

9.64E-12 – 3.15E-02

113

5 Cellular growth and proliferation

1.16E-11 – 3.15E-02

204

  1. Top five bio-functional categories identified by IPA software by analysing the 1,173 transcripts modulated in 10 μM D6 treated LB24 melanoma cells are reported. The p-value reflects the significance of the enrichment of input genes in each functional category. The complete list is reported in Additional File 1-B.
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Molecular Cancer

ISSN: 1476-4598