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Table 4 Melanoma modulated genes

From: Molecular changes induced by the curcumin analogue D6 in human melanoma cells

GENE

FC

 

LB

BJ

HSPA6

368.61

480.00

HSPA1A

20.35

12.38

CDKN1A

19.35

4.29

DDIT3

11.11

9.11

GADD45A

7.78

6.00

GADD45B

7.47

14.90

PMAIP1

6.08

7.72

BCL10

3.93

2.02

TP53BP2

2.36

–

CCNF

0.24

–

KIT

0.30

–

CDK4

0.43

0.43

CCNB1

0.43

–

CDC25B

0.47

–

NFKB1

0.47

–

PIK3R2

0.48

–

  1. Genes differentially expressed in LB24 melanoma cells after D6 treatment are reported. The most significant genes possibly related to D6 antiproliferative and pro-apoptotic effects as well as their relative fold change values (FC) in either LB24 melanoma cells or BJ fibroblasts are presented. The complete lists of differentially expressed genes and relative FC for each cell line are reported in the Additional files 1-A and 2-A respectively.
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Molecular Cancer

ISSN: 1476-4598