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Figure 3 | Molecular Cancer

Figure 3

From: 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

Figure 3

FICZ upregulates RA-dependent signaling intermediates. Cell lysates collected at 48 h time point were resolved on 12% polyacrylamide gels. 25 μg protein was loaded per well. FICZ upregulates the amount of c-Cbl and IRF-1 expression and pY507 Lyn and pY1021 PDGFRβ phospho-protein. Total RARα expressed is not upregulated, nor is the GAPDH loading control.

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Molecular Cancer

ISSN: 1476-4598