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Figure 2 | Molecular Cancer

Figure 2

From: Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis

Figure 2

The apoptotic effect of FKB on OS cells. A, 143B cells were treated with different concentrations of FKB for 24 h. Apoptosis was evaluated by DAPI staining. B, 143B and Saos-2 cells were stained with annexin V and propidium iodide and analyzed by flow-cytometry. C, The chart illustrates the results from three separate experiments of flow-cytomety. D, FKB treatment induced the expression of Fas, Bax, Puma, and decreased Survivin and Bcl-2 expression. Cells were treated for 24 h and protein was resolved by SDS-PAGE with GAPDH as a control.

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