Table 1 Immunohistochemical results for 4 cases
Patient id | Original IHC results | New IHC results | Cancer Origin Test™results | Lung Cancer Test™results | Clinical Dx prior to new IHC | Results (Final Clinical Dx) |
|---|---|---|---|---|---|---|
12432 | CK7(+), CK8(+), CK19(+), CA125(+), PR (+), CK20(-), CEA(-), TTF1(-), CA19-9(-), VIMENTIN(-) | CK5/6(+, focally), MESOTHELIN(+), CALRETININ(+), EMA(-), LEUM1(-) | Pleural mesothelioma | peritoneal ovarian carcinoma | Peritoneal mesothelioma | |
12412 | none performed | CK 7(+), CK20(-), CA125(+), ER(-), PR(-), CEA(-), p63(-) | Ovarian carcinoma | SCC of the Head & Neck of skin | Ovary peritoneal caricnoma | |
11826 | none performed | CK7 (+), ER(-), PR(-),GCDFP15(-), S-100(-)(rare cells with only weak cytoplasmic immunoreactivity, therefore this staining was considered negative), CEA(-), EMA(+), p63(-), 34E12(+) | Breast carcinoma or SCC of the Anus or Skin | Lung adenocarcinoma or pancreatic adenocarcinoma | Lung adenocarcinoma or pancreatic adenocarcinoma | |
11805 | CK positive and Vimentin negative | TTF1(+), CK7(+, focally), CK20(-), CHROMOGRANIN(+), SYNAPTOPHYSIN(+), CK13(-), CK14(-), CD56(+) | Lung small cell carcinoma or lung adenocarcinoma | Lung small cell carcinoma | Lung adenocarcinoma or pancreatic adenocarcinoma | Lung small cell carcinoma |