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Table 1 Upregulated genes from microarray with fold change >1.6 and p < 0.05

From: Global profiling of prolactin-modulated transcripts in breast cancer in vivo

 

Unigene

Symbol

Gene descriptor

Fold change

1

Hs.89626

PTHrP

parathyroid hormone-like hormone

11.9

2

Hs.473539

BACH1

BTB and CNC homology 1, basic leucine zipper transcription factor 1

5.2

3

Hs.46468

CCR6

chemokine (C-C motif) receptor 6

4.9

4

Hs.314676

ITCH

itchy homolog E3 ubiquitin protein ligase

4.2

5

Hs.150744

INVS

inversin

3.8

6

Hs.387222

NEK6

NIMA (never in mitosis gene a)-related kinase 6

3.8

7

Hs.76095

IER3

immediate early response 3

3.4

8

Hs.121520

AMIGO2

amphoterin induced gene 2

3.3

9

Hs.115263

EREG

epiregulin

3.2

10

Hs.436186

ERAP1

type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

3.0

11

Hs.99037

CTEN

C-terminal tensin-like

3.0

12

Hs.252855

MFI2

antigen p97 (melanoma associated)

2.9

13

Hs.439658

MGC4796

Ser/Thr-like kinase

2.8

14

Hs.417962

DUSP4

dual specificity phosphatase 4

2.7

15

Hs.8257

CISH

cytokine inducible SH2-containing protein

2.6

16

Hs.660427

PAR5

Prader-Willi/Angelman syndrome-5

2.6

17

Hs.279887

AIPL1

aryl hydrocarbon receptor interacting protein-like 1

2.6

18

Hs.145807

TMC5

transmembrane channel-like 5

2.5

19

Hs.512708

TGM2

transglutaminase 2

2.4

20

Hs.270833

AREG

amphiregulin (schwannoma-derived growth factor)

2.4

21

Hs.170623

FGD6

FYVE, RhoGEF and PH domain containing 6

2.3

22

Hs.418138

FN1

fibronectin 1

2.3

23

Hs.102541

NTN4

netrin 4

2.2

24

Hs.354906

RAB39

RAB39, member RAS oncogene family

2.2

25

Hs.443906

EGLN3

egl nine homolog 3 (C. elegans)

2.2

26

Hs.149156

GLDC

glycine dehydrogenase

2.2

27

Hs.1145

WT1

Wilms tumor 1

2.1

28

Hs.25220

LARGE

like-glycosyltransferase

2.1

29

Hs.282557

CP

ceruloplasmin (ferroxidase)

2.0

30

Hs.78909

ZFP36L2

zinc finger protein 36, C3H type-like 2

2.0

31

Hs.413297

RGS16

regulator of G-protein signalling 16

2.0

32

Hs.182454

NYREN18

NEDD8 ultimate buster-1

2.0

33

Hs.96125

RCP

Rab coupling protein

2.0

34

Hs.308028

TMEM17

transmembrane protein 17

2.0

35

Hs.21894

PPM1H

protein phosphatase 1H (PP2C domain containing)

2.0

36

Hs.240395

KCNK6

potassium channel, subfamily K, member 6

1.9

37

Hs.36563

B7-H4

immune costimulatory protein B7-H4

1.9

38

Hs.27345

RNGTT

RNA guanylyltransferase and 5’-phosphatase

1.9

39

Hs.144287

HEY2

hairy/enhancer-of-split related with YRPW motif 2

1.8

40

Hs.269857

HRB2

HIV-1 rev binding protein 2

1.8

41

Hs.387871

TNFSF10

tumor necrosis factor (ligand) superfamily, member 10

1.8

42

Hs.80409

GADD45A

growth arrest and DNA-damage-inducible, alpha

1.8

43

Hs.134742

FAM20C

family with sequence similarity 20, member C

1.8

44

Hs.274701

TK2

thymidine kinase 2, mitochondrial

1.8

45

Hs.55610

SLC30A1

solute carrier family 30 (zinc transporter), member 1

1.8

46

Hs.82173

TIEG

TGFB inducible early growth response

1.8

47

Hs.404081

FGFR2

fibroblast growth factor receptor 2

1.8

48

Hs.31218

SCAMP1

secretory carrier membrane protein 1

1.8

49

Hs.350470

TFF1

trefoil factor 1

1.8

50

Hs.95655

SECTM1

secreted and transmembrane 1

1.8

51

Hs.902

NF2

neurofibromin 2

1.7

52

Hs.310640

T2BP

TRAF2 binding protein

1.7

53

Hs.252550

TNIK

TRAF2 and NCK interacting kinase

1.7

54

Hs.6838

ARHE

ras homolog gene family, member E

1.7

55

Hs.418062

B3GALT3

betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3

1.7

56

Hs.270411

PLEKHC1

pleckstrin homology domain containing, family C member 1

1.7

57

Hs.647388

ARHGDIG

Rho GDP dissociation inhibitor (GDI) gamma

1.7

58

Hs.202453

MYC

v-myc myelocytomatosis viral oncogene homolog (avian)

1.6

59

Hs.110488

CHSY1

carbohydrate (chondroitin) synthase 1

1.6

60

Hs.9795

ACOX2

acyl-Coenzyme A oxidase 2, branched chain

1.6

61

Hs.158357

UNC5CL

unc-5 homolog C (C. elegans)-like

1.6

62

Hs.441972

IFNT1

interferon tau-1

1.6

63

Hs.221889

CSDA

cold shock domain protein A

1.6

64

Hs.333503

RNF38

ring finger protein 38

1.6

65

Hs.203581

DDX54

DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

1.6

66

Hs.345226

ZNF563

zinc finger protein 563

1.6

67

Hs.30991

ANKRD6

ankyrin repeat domain 6

1.6

68

Hs.4113

AHCYL1

S-adenosylhomocysteine hydrolase-like 1

1.6

69

Hs.416077

SEMA4B

sema domain

1.6

70

Hs.7378

PHLDB2

pleckstrin homology-like domain, family B, member 2

1.6

71

Hs.369063

ZIC2

Zic family member 2 (odd-paired homolog, Drosophila)

1.6

72

Hs.515284

ZNF505

zinc finger protein 505

1.6

73

Hs.426511

MIPOL1

mirror-image polydactyly 1

1.6

74

Hs.108966

PIP5K2A

phosphatidylinositol-4-phosphate 5-kinase, type II, alpha

1.6

75

Hs.432607

PSMB2

proteasome (prosome, macropain) subunit, beta type, 2

1.6