Molecular Cancer

Table 2 Downregulated genes from microarray with fold change > −1.6 and p < 0.05

From: Global profiling of prolactin-modulated transcripts in breast cancer in vivo

	Unigene	Symbol	Gene descriptor	Fold Change
1	Hs.275464	KLK10	kallikrein 10	−3.3
2	Hs.307030	KRTAP1-5	keratin associated protein 1-5	−3.3
3	Hs.282233	MLLT6	myeloid/lymphoid leukemia translocated to, 6	−3.2
4	Hs.78518	NPR2	natriuretic peptide receptor B/guanylate cyclase B	−2.8
5	Hs.155024	BCL6	B-cell CLL/lymphoma 6	−2.8
6	Hs.90800	MMP16	matrix metalloproteinase 16 (membrane-inserted)	−2.5
7	Hs.87539	ALDH3B2	aldehyde dehydrogenase 3 family, member B2	−2.4
8	Hs.144906	METAP2	methionyl aminopeptidase 2	−2.3
9	Hs.440455	ALAS2	aminolevulinate, delta-, synthase 2	−2.2
10	Hs.266175	PAG	phosphoprotein associated with glycosphingolipid-enriched microdomains	−2.2
11	Hs.435947	RBM15	RNA binding motif protein 15	−2.2
12	Hs.233325	HFE	hemochromatosis	−2.1
13	Hs.443012	SEMA6A	sema domain,transmembrane domain(TM),and cytoplasmic domain,(semaphorin)6A	−2.0
14	Hs.357901	SOX4	SRY (sex determining region Y)-box 4	−2.0
15	Hs.415048	FLT4	fms-related tyrosine kinase 4	−2.0
16	Hs.380833	IGFBP5	insulin-like growth factor binding protein 5	−1.9
17	Hs.444881	CRAMP1L	Crm, cramped-like (Drosophila)	−1.9
18	Hs.398124	DNAH5	dynein, axonemal, heavy polypeptide 5	−1.9
19	Hs.79025	SNRK	SNF-1 related kinase	−1.9
20	Hs.432121	PRDX2	peroxiredoxin 2	−1.9
21	Hs.22370	NEXN	nexilin (F actin binding protein)	−1.9
22	Hs.144914	GNMT	glycine N-methyltransferase	−1.9
23	Hs.21446	CENTB5	centaurin, beta 5	−1.9
24	Hs.58103	AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	−1.8
25	Hs.387385	SMURF2	E3 ubiquitin ligase SMURF2	−1.8
26	Hs.324470	ADD3	adducin 3 (gamma)	−1.8
27	Hs.348387	GSTM4	glutathione S-transferase M4	−1.8
28	Hs.58419	TARSH	target of Nesh-SH3	−1.7
29	Hs.174051	SNRP70	small nuclear ribonucleoprotein 70 kDa polypeptide (RNP antigen)	−1.7
30	Hs.211601	MAP3K12	mitogen-activated protein kinase kinase kinase 12	−1.7
31	Hs.23964	SAP18	sin3-associated polypeptide, 18 kDa	−1.7
32	Hs.380929	LDHD	lactate dehydrogenase D	−1.7
33	Hs.390568	ZNF585A	zinc finger protein 585A	−1.7
34	Hs.241305	TRIM16	tripartite motif-containing 16	−1.7
35	Hs.403933	FBXO32	F-box only protein 32	−1.7
36	Hs.434756	AP2E	adaptor-related protein complex 2, epsilon subunit	−1.7
37	Hs.173894	CSF1	colony stimulating factor 1 (macrophage)	−1.6
38	Hs.104555	NPFF	neuropeptide FF-amide peptide precursor	−1.6
39	Hs.307015	KRTAP4-14	keratin associated protein 4-14	−1.6
40	Hs.301961	GSTM1	glutathione S-transferase M1	−1.6
41	Hs.307915	ABCC4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	−1.6
42	Hs.512000	GP1BB	glycoprotein Ib (platelet), beta polypeptide	−1.6
43	Hs.446297	ZNF498	zinc finger protein 498	−1.6
44	Hs.120396	FRMD4	FERM domain containing 4	−1.6
45	Hs.222901	GRIK4	glutamate receptor, ionotropic, kainate 4	−1.6
46	Hs.464896	ZNF397	zinc finger protein 397	−1.6
47	Hs.16232	CNKSR1	connector enhancer of kinase suppressor of Ras 1	−1.6
48	Hs.255526	DTNA	dystrobrevin, alpha	−1.6
49	Hs.107203	PLAC2	placenta-specific 2	−1.6
50	Hs.9029	KRT23	keratin 23 (histone deacetylase inducible)	−1.6
51	Hs.91753	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	−1.6
52	Hs.331555	SPINK5	serine protease inhibitor, Kazal type 5	−1.6
53	Hs.391858	TIA1	TIA1 cytotoxic granule-associated RNA binding protein	−1.6
54	Hs.109122	MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	−1.6
55	Hs.445072	ARGBP2	Arg/Abl-interacting protein ArgBP2	−1.6

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