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Table 4 Gene Ontology (GO) analysis of PRL upregulated genes with false discovery rate (FDR) < 25

From: Global profiling of prolactin-modulated transcripts in breast cancer in vivo

GO Term

Description

P value

FDR

GO:0030005

cellular di-, tri-valent inorganic cation homeostasis

0.002

2.452

GO:0042592

homeostatic process

0.002

2.848

GO:0055066

di-, tri-valent inorganic cation homeostasis

0.002

3.079

GO:0030003

cellular cation homeostasis

0.003

4.015

GO:0055080

cation homeostasis

0.004

6.550

GO:0006879

cellular iron ion homeostasis

0.006

8.210

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

0.006

9.136

GO:0060249

anatomical structure homeostasis

0.008

10.970

GO:0055072

iron ion homeostasis

0.008

11.045

GO:0019725

cellular homeostasis

0.008

11.791

GO:0043122

regulation of I-kappaB kinase/NF-kappaB cascade

0.008

11.809

GO:0048514

blood vessel morphogenesis

0.009

12.950

GO:0051052

regulation of DNA metabolic process

0.010

13.580

GO:0042127

regulation of cell proliferation

0.010

13.992

GO:0043066

negative regulation of apoptosis

0.011

15.532

GO:0043069

negative regulation of programmed cell death

0.012

16.371

GO:0060548

negative regulation of cell death

0.012

16.542

GO:0048878

chemical homeostasis

0.013

17.642

GO:0006873

cellular ion homeostasis

0.014

18.854

GO:0055082

cellular chemical homeostasis

0.014

19.975

GO:0001568

blood vessel development

0.015

20.556

GO:0010627

regulation of protein kinase cascade

0.015

20.807

GO:0001944

vasculature development

0.016

22.079