Figure 7
From: Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers
Inhibitory activity of anti-Nectin-2 mAbs on Nectin-2-Nectin-2 and Nectin-2-Nectin-3 interaction. Inhibitory activity of anti-Nectin-2 mAbs on Nectin-2-Nectin-2 interaction and Nectin-2-Nectin-3 interaction were measured by using an ELISA-based time-resolved fluorescence spectroscopy assay and a Biacore assay, respectively. The percentage inhibition of Nectin-2-Nectin-2 or Nectin-2-Nectin-3 interaction on the vertical axis was calculated as described in Methods.