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Table 2 Multivariate Cox regression analysis of BCL11A and survival in patients with early stage cancer (IA–IIB)

From: BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification

Variable

Hazards ratio (95% CI)

Unfavorable / favorable

P value

OS

   

Age

1.07 (1.03– 1.12)

≥ 60/< 60

0.002

Tumor size

1.29 (1.08– 1.57)

≥ 3 cm/< 3 cm

0.007

Lymph node status

9.09 (3.58– 23.8)

Positive/negative

0.000

Performance status

2.46 (1.06– 5.68)

1-2/0

0.036

BCL11A protein

0.27 (0.11– 0.69)

Higher/lower

0.006

Histological type

  

0.003

SCC#

0.16 (0.05– 0.54)

SCC/AC

0.003

LCC※

0.10 (0.03– 0.38)

LCC/AC

0.001

DFS

   

Tumor size

1.32 (1.11– 1.56)

≥ 3 cm/< 3 cm

0.002

Lymph node status

2.56 (1.32– 5.00)

Positive/negative

0.006

BCL11A protein

0.25 (0.12– 0.51)

Higher/lower

0.001

  1. #SCC vs. AC; ※LCC vs. AC.