Figure 5
From: Role of SIRT3 in the regulation of redox balance during oral carcinogenesis
Sequence chromatograms of DNA isolated from a patient with OSCC. (A) Region harboring the s.477G > A mutation in patient OSCC_32. Left, heterozygous mutation in normal DNA; Right, heterozygous mutation in tumor DNA. (B) Region harboring the c.622G > A mutation (p.Val208Ile) carried by patient OSCC_32.Left, heterozygous mutation in normal DNA; Middle, heterozygous mutation in tumor DNA; Right, predominance of expression of the mutated allele in cDNA synthesized from OSCC_32 tumor RNA.