Figure 1
From: A gene expression profile indicative of early stage HER2 targeted therapy response
Differential gene expression of the five genes in response to 1 μM lapatinib and a) 150 nM afatinib b) 150 nM neratinib treatment. Assessing the 3 cell lines shows that the response to afatinib is similar to the response profile of lapatinib. N=3 b) Differential expression of the five genes in response to 1 μM lapatinib and 150 nM neratinib. Analysis across the 3 cell lines shows that the response to neratinib is similar to the response profile of lapatinib. N=3 * indicates p < 0.05, ** indicates p < 0.01, *** indicates p < 0.005.