Figure 3

The clonality and size of V δ 5 T cells in a patient with T-ALL at different time points. Vδ5 T cell clonality was measured at different time points including the following: A: relapse before allo-HSCT (the monoclonal Vδ5 product size was 466 bp), B: pre-HSCT, C: 4 weeks post allo-HSCT, D: 8 weeks post allo-HSCT, E: 68 weeks post allo-HSCT (the clonal Vδ5 products were 459 and 477 bp, there were different from the malignant T cell clone with 466 bp), F: 100 weeks post allo-HSCT and disease relapse (a 466 bp monoclonal Vδ5 product is again observed), and G: 108 weeks post allo-HSCT and after one chemotherapy cycle with minimal residual disease (MRD) remaining (a 466 bp monoclonal Vδ5 product is still detectable). H: The expression level of the monoclonal the Vδ5 gene at different time points (i.e., relapse before allo-HSCT, relapse at 100 and 108 weeks post allo-HSCT and after one chemotherapy cycle with MRD remaining).