Risk groups1 | HPV16 status | Patients | Controls | Adj. OR (95% CI)2 | |||
---|---|---|---|---|---|---|---|
(n = 325) | (n = 335) | ||||||
No. | % | No. | % | OSCC | SCCOP | ||
Never-smokers | (n = 99) | (n = 96) | |||||
Low-risk group | − | 15 | 15.2 | 32 | 33.3 | 1.0 | 1.0 |
Medium-risk group | − | 17 | 17.2 | 38 | 39.6 | 1.0 (0.4 − 2.3) | 1.0 (0.2 − 3.1) |
High-risk group | − | 21 | 21.2 | 18 | 18.8 | 2.3 (1.0 − 5.9) | 2.5 (1.0 − 8.6) |
Low-risk group | + | 10 | 10.1 | 5 | 5.2 | 5.4 (1.5 − 19.4) | 11.0 (2.6 − 46.8) |
Medium-risk group | + | 11 | 11.1 | 1 | 1.0 | 28.4 (3.2 − 250.2) | 51.6 (5.4 − 496.8) |
High-risk group | + | 25 | 25.3 | 1 | 2.1 | 35.6 (7.0 − 180.3) | 67.4 (12.0 − 378.5) |
Ever-smokers | (n = 226) | (n = 239) | |||||
Low-risk group | − | 46 | 20.4 | 49 | 20.5 | 1.0 | 1.0 |
Medium-risk group | − | 36 | 15.9 | 91 | 38.1 | 0.4 (0.2 − 0.7) | 0.5 (0.2 − 1.0) |
High-risk group | − | 90 | 39.8 | 65 | 27.2 | 1.5 (0.9 − 2.6) | 1.5 (0.8 − 2.9) |
Low-risk group | + | 17 | 7.5 | 8 | 3.4 | 2.2 (0.8 − 5.6) | 3.6 (1.3 − 10.0) |
Medium-risk group | + | 12 | 5.3 | 20 | 8.4 | 0.7 (0.3 − 1.5) | 1.2 (0.5 − 3.1) |
High-risk group | + | 25 | 11.1 | 6 | 2.5 | 4.8 (1.8 − 12.9) | 7.4 (2.6 − 21.4) |