Figure 6From: FGFR3 has tumor suppressor properties in cells with epithelial phenotypeFGFR3 actions in pancreatic cancers: a working model. FGFR3 action in cancer cells from epithelial origin limits tumor growth. During tumor progression, FGFR3 disruption or loss of expression promotes cell growth. If epithelial to mesenchymal transition occurs, then FGFR3 will function as an oncogene favoring tumor progression.Back to article page