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Table 1 Positions of Phosphorylations of RelA and corresponding kinases

From: The complexity of NF-κB signaling in inflammation and cancer

Kinase p65 target residue Effect of phosphate References
unknown S205 stimulates transcriptional activity [54]
MSK1 S276 stimulates transcriptional activity [55]
PIM1 S276 stimulates transcriptional activity [56]
PKAc S276 stimulates transcriptional activity [57, 58]
unknown S281 stimulates transcriptional activity [54]
PKCζ S311 stimulates transcriptional activity [59]
GSK-3β S468 stimulates transcriptional activity [60]
IKK2 S468; S536 stimulates transcriptional activity and nuclear import [61, 62]
IKKϵ S468;S536 stimulates transcriptional activity [63, 64]
CKII S529 stimulates transcriptional activity [65]
CaMKIV S535 stimulates transcriptional activity [66]
TBK1 S536 stimulates transcriptional activity [67]
IKK1 S536 stimulates transcriptional activity and stabilization [68]
RSK1 S536 decreases IκBα -mediated nuclear export [69]
ATM S547 Increased expression of specific genes [70]
unknown T254 stabilization and nuclear localization [71]
unknown T435 stimulates transcriptional activity [72]
CHK1 T505 pro-apoptotic effect [73]