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Figure 5 | Molecular Cancer

Figure 5

From: Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines

Figure 5

Combined use of FTI-277 and PAK inhibitor IPA3 reduce proliferation of A375MM, HT29, A549 cells but not of HeLa or MCF7 cells. Effects of FTI-277 and/or IPA3 on cell proliferation in the indicated cells.% is relative to the vehicle that was considered as 100%. Error bars indicate means ± SD of 3 independent experiments from 5 wells. The statistical significance of the treatments was calculated using t-test as described in Methods: ns = not significant, p-value >0.05; * = significant, p-value <0.05; ** highly significant = p-value <0.01; *** very highly significant = p-value < 0.001; **** highest significance = p-value < 0.0001.

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Molecular Cancer

ISSN: 1476-4598