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Table 1 Examples of IMIDs associated with increased risks for cancer

From: Cancer risk in immune-mediated inflammatory diseases (IMID)

IMID Associated malignancies
Aplastic anemia Myeloproliferative disorders [36]
Autoimmune hepatitis Non-melanoma skin cancer, hepatocellular carcinoma [37, 38]
Celiac disease Non-Hodgkin’s lymphoma, esophageal cancer, Hodgkin’s lymphoma, small bowel carcinoma, stomach cancer [3941]
Crohn’s disease Colorectal and fistula cancer and for cancer of the small bowel, upper gastrointestinal tract, lung, urinary bladder and skin [4244]. Liver, pancreatic, prostate, testicular, and kidney cancers, nonthyroid endocrine tumors, and leukemia [45].
Dermatomyositis Ovarian, lung, gastric cancer [46]
Giant cell arteritis Myeloproliferative disorders [36]
Immune thrombocytopenic purpura Myeloproliferative disorders [36]
Polymyalgia rheumatica Myeloproliferative disorders [36]
Primary biliary cirrhosis Hepatocellular carcinoma [38]
Psoriasis Colon cancer [47] and possibly cancer of the urinary bladder, kidney, oropharynx/larynx, esophagus, stomach, liver/gallbladder, vulva, female breast, and pancreas and for leukemia, non-Hodgkin’s lymphoma, and non-melanoma skin cancer [4857]
Reiter’s syndrome Myeloproliferative disorders [36]
RA Lymphoma and leukemia, non-melanoma skin cancers [32, 33, 58]; lymphoma and lung cancer [33]
Sarcoidosis Rectal, colon, kidney, skin (squamous cell), nonthyroid endocrine cancer; non-Hodgkin’s lymphoma; leukemia [59]
Sjögren syndrome lymphoproliferative disorders [46]
SLE Hematological malignancies, including non-Hodgkin’s lymphoma, and cancers of the vagina/vulva/cervix, nasopharynx, and kidney [6062]
Systemic sclerosis Lung, skin, esophageal, non-melanoma skin, and liver cancer [40, 46, 63]
Type 1 diabetes mellitus Pancreatic cancer [64, 65]
Ulcerative colitis Colorectal carcinoma, liver-biliary cancer, and leukemia [42, 66]
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