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Figure 7 | Molecular Cancer

Figure 7

From: Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway

Figure 7

Effects of MELK on tumor growth, peritoneal spreading and metastasis in vivo. A, Photographs of tumors derived from NCI-N87/nc-shRNA and NCI-N87/MELK-shRNA cells and growth curves of tumors in nude mice (*P < 0.05; n = 5 per group). Tumor diameters were measured every 5 days. B, Average weights of tumors in nude mice (**P < 0.01). C and D, Effects of MELK knockdown on peritoneal spreading and metastasis (**P < 0.01; n = 10 per group). Metastatic nodules were obvious in the control group as indicated by the red arrows. E, Representative photographs of immunohistochemical analysis of Ki-67 antigen and MELK protein in tumors of nude mice (original magnification, 200X).

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Molecular Cancer

ISSN: 1476-4598