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Table 1 Representative gene expression profile of different cell populations[23] in Matrigel plugs from Dusp3-knockout versus WT

From: DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase

Gene name

Alternative names

Ratio Dusp3-KO/WT

P value

Endothelial cells

Pecam1

Cd31; PECAM-1

0.52

0.045*

Mcam

CD146; CD149

0.46

0.060

Tie1

TIE; tie-1

0.37

0.059

Cdh5

VECD; Cd144; VE-Cad;

0.35

0.038*

Pericytes

Cspg4

AN2; NG2

0.76

0.25

Pdgfrb

CD140b; PDGFR-1

0.66

0.047*

Acta2

a-SMA; alphaSMA

0.29

0.034*

Lymphoid and Myeloid markers

Csf1r

CD115; CSF-1R

1.2

0.58

Itgam

MAC1; Cd11b; CD11b/CD18

1.1

0.31

Klrb1c

CD161; NK1.1

1.1

0.85

Ly6a/e

Sca1; Ly-6A.2

1.1

0.56

Ly6c1

Ly6c

1.1

0.56

Emr1

F4/80

1.0

0.95

Lgals3

Mac-2

1.0

0.58

Csf1r

CD115; CSF-1R

1.0

0.97

  1. Data presented are extracted from a genome-wide microarray dataset obtained using Illumina’s multi sample format Mouse WG-6 V2 BeadChip. Data are presented as the ratio of the average values obtained from 2 pools of 3 Dusp3-knockout each on 2 pools of 3 WT mice each and the corresponding p-value. (*p < 0.05 determined using unpaired student’s t test).