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Table 1 Representative gene expression profile of different cell populations[23] in Matrigel plugs from Dusp3-knockout versus WT

From: DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase

Gene name Alternative names Ratio Dusp3-KO/WT P value
Endothelial cells
Pecam1 Cd31; PECAM-1 0.52 0.045*
Mcam CD146; CD149 0.46 0.060
Tie1 TIE; tie-1 0.37 0.059
Cdh5 VECD; Cd144; VE-Cad; 0.35 0.038*
Pericytes
Cspg4 AN2; NG2 0.76 0.25
Pdgfrb CD140b; PDGFR-1 0.66 0.047*
Acta2 a-SMA; alphaSMA 0.29 0.034*
Lymphoid and Myeloid markers
Csf1r CD115; CSF-1R 1.2 0.58
Itgam MAC1; Cd11b; CD11b/CD18 1.1 0.31
Klrb1c CD161; NK1.1 1.1 0.85
Ly6a/e Sca1; Ly-6A.2 1.1 0.56
Ly6c1 Ly6c 1.1 0.56
Emr1 F4/80 1.0 0.95
Lgals3 Mac-2 1.0 0.58
Csf1r CD115; CSF-1R 1.0 0.97
  1. Data presented are extracted from a genome-wide microarray dataset obtained using Illumina’s multi sample format Mouse WG-6 V2 BeadChip. Data are presented as the ratio of the average values obtained from 2 pools of 3 Dusp3-knockout each on 2 pools of 3 WT mice each and the corresponding p-value. (*p < 0.05 determined using unpaired student’s t test).