|
Clinicopathologic features
|
Total no. of patients, n = 60
|
No. of patients
|
P
|
|---|
|
Fbxw7 negative
|
Fbxw7 positive
|
|---|
|
Age (y)
|
<50
|
19
|
13
|
6
|
0.365
|
|
≥50
|
41
|
23
|
18
|
|
Sex
|
Male
|
48
|
28
|
20
|
0.598
|
|
Female
|
12
|
8
|
4
|
|
HBV
|
Absent
|
14
|
9
|
5
|
0.709
|
|
Present
|
46
|
27
|
19
|
|
Serum AFP level (ng/mL)
|
<400
|
24
|
14
|
10
|
0.830
|
|
≥400
|
36
|
22
|
14
|
|
Tumor size (cm)
|
<5
|
21
|
7
|
14
|
0.002*
|
|
≥5
|
39
|
29
|
10
|
|
No. of tumor nodules
|
1
|
45
|
24
|
21
|
0.068
|
|
≥2
|
15
|
12
|
3
|
|
Cirrhosis
|
Absent
|
28
|
17
|
11
|
0.916
|
|
Present
|
32
|
19
|
13
|
|
Venous infiltration
|
Absent
|
31
|
14
|
17
|
0.015*
|
|
Present
|
29
|
22
|
7
|
|
Edmondson-Steiner grading
|
I + II
|
18
|
6
|
12
|
0.006*
|
|
III + IV
|
42
|
30
|
12
|
|
TNM tumor stage
|
I + II
|
40
|
19
|
21
|
0.005*
|
|
III + IV
|
20
|
17
|
3
|
- HCC, hepatocellular carcinoma; HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis. *Statistically significant.
