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Table 2 Multivariate Cox regression analysis of the overall and disease-free 5-year survival of 60 HCC patients

From: Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma

Variables Overall survival Disease-free survival
HR 95% CI P HR 95% CI P
Age 2.113 0.888-5.030 0.091 1.670 0.787-3.545 0.182
Sex 0.749 0.339-1.652 0.474 1.031 0.492-2.162 0.936
HBV 1.846 0.694-4.908 0.219 1.971 0.827-4.696 0.126
No. of tumor nodules 1.092 0.500-2.386 0.824 0.889 0.438-1.805 0.744
Tumor size 0.411 0.160-1.056 0.065 0.481 0.211-1.098 0.082
Venous infiltration 1.539 0.722-3.284 0.264 1.892 0.940-3.808 0.074
Serum AFP level 0.883 0.412-1.895 0.749 0.953 0.483-1.880 0.889
Cirrhosis 1.288 0.651-2.548 0.468 1.313 0.711-2.423 0.384
Edmondson-Steiner grading 0.771 0.322-1.846 0.560 0.702 0.338-1.458 0.342
TNM tumor stage 3.576 1.251-10.211 0.017* 3.532 1.266-9.858 0.016*
Fbxw7 expression in tumor 0.253 0.081-0.790 0.018* 0.228 0.078-0.666 0.007*
  1. HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis; HR, hazard ratio; CI, confidence interval. *Statistically significant.