Table 1 Clinical characteristics of NPC patients according to high and low CIP2A expression
Characteristics | No. of patients | Expression of CIP2A | P value | |
|---|---|---|---|---|
| Â | Â | Low, n (%) | High, n (%) | Â |
Age | Â | Â | Â | Â |
≤45 | 130 | 48 (50) | 82 (45) | 0.39 |
>45 | 150 | 48 (50) | 102 (55) | Â |
Sex | Â | Â | Â | Â |
Male | 208 | 72 (75) | 136 (74) | 0.84 |
Female | 72 | 24 (25) | 48 (26) | Â |
WHO type | Â | Â | Â | Â |
I + II | 10 | 2 (2) | 8 (6) | 0.50 |
III | 270 | 94 (98) | 176 (94) | Â |
VCA-IgA | Â | Â | Â | Â |
< 1:80 | 41 | 16 (17) | 25 (14) | 0.49 |
≥ 1:80 | 239 | 80 (83) | 159 (86) |  |
EA-IgA | Â | Â | Â | Â |
< 1:10 | 68 | 24 (25) | 44 (24) | 0.84 |
≥ 1:10 | 212 | 72 (75) | 140 (76) |  |
T Stage | Â | Â | Â | Â |
T1-T2 | 137 | 55 (57) | 82 (45) | 0.04 |
T3-T4 | 143 | 41 (43) | 102 (55) | Â |
N Stage | Â | Â | Â | Â |
N0-N1 | 173 | 61 (64) | 112 (61) | 0.66 |
N2-N3 | 107 | 35 (36) | 72 (39) | Â |
TNM Stage | Â | Â | Â | Â |
I-II | 86 | 40 (42) | 46 (25) | <0.01 |
III-IV | 194 | 56 (58) | 138 (75) | Â |
Locoregional failure | Â | Â | Â | Â |
Yes | 38 | 11 (11) | 27 (15) | 0.46 |
No | 242 | 85 (89) | 157 (85) | Â |
Distant metastasis | Â | Â | Â | Â |
Yes | 63 | 11 (11) | 52 (28) | <0.01 |
No | 217 | 85 (89) | 132 (72) | Â |
Death | Â | Â | Â | Â |
Yes | 67 | 14 (15) | 53 (29) | 0.01 |
No | 213 | 82 (85) | 131 (71) | Â |