Skip to main content

Table 2 Univariate and multivariable Cox regression analyses of CIP2A expression levels and survival rates

From: Overexpression of CIP2A is an independent prognostic indicator in nasopharyngeal carcinoma and its depletion suppresses cell proliferation and tumor growth

 

Univariate analysis

Multivariate analysis

Variable

HR

95% CI

P- value

HR

95% CI

P- value

  

Overall survival

   

CIP2A expression (High vs. Low)

2.13

1.18-3.84

0.012

1.85

1.02-3.35

0.042

TNM stage (III-IV vs. I-II)

3.16

1.57-6.39

0.001

2.87

1.42-5.82

0.003

Sex (Male vs. Female)

1.57

0.86-2.87

0.146

   

Age (>45 years vs. ≤45 years)

1.43

0.87-2.34

0.155

   

WHO type (III vs. I + II)

0.81

0.26-2.58

0.722

   

VCA-IgA (≥1:80 vs. < 1:80)

1.80

0.78-4.17

0.168

   

EA-IgA (≥1:10 vs. < 1:10)

1.19

0.66-2.15

0.555

   
  

Disease-free survival

   

CIP2A expression (High vs. Low)

1.92

1.16-3.17

0.011

1.70

1.03-2.82

0.039

TNM stage (III-IV vs. I-II)

2.87

1.59-5.17

<0.001

2.59

1.43-4.69

0.002

Sex (Male vs. Female)

1.57

0.93-2.68

0.094

   

Age (>45 years vs. ≤45 years)

1.25

0.82-1.93

0.301

   

WHO type (III vs. I + II)

0.78

0.29-2.12

0.622

   

VCA-IgA (≥1:80 vs. < 1:80)

2.06

0.95-4.46

0.068

   

EA-IgA (≥1:10 vs. < 1:10)

1.44

0.84-2.48

0.190

   
Back to article page

Molecular Cancer

ISSN: 1476-4598