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Table 1 Acetylated proteins more than two-fold up regulated by nutlin-3 detected by SILAC-based mass spectrometry

From: Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia

Accession number

Protein IDs

Name

Number of peptides

Sequence Coverage, %

Ratio of H/L, normalized

P04792

IPI00025512

Hsp27/HSPB1

2

12.7

2.0741

B4DR52

IPI00646240

Histone H2B

2

14.5

2.3519

Q13765

IPI00797126

Alpha-NAC

4

5.9

3.4854

  1. Abbreviations: Alpha-NAC Nascent polypeptide-associated complex subunit alpha, Hsp27 Heat shock protein 27, HSBP1 Heat shock protein beta-1, H/L ratio between proteins abundance in cells labeled with heavy isotopes compared to cells labeled with light isotopes, SILAC stable isotope labeling with amino acids in cell culture.
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Molecular Cancer

ISSN: 1476-4598