Skip to main content

Table 1 Acetylated proteins more than two-fold up regulated by nutlin-3 detected by SILAC-based mass spectrometry

From: Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia

Accession number Protein IDs Name Number of peptides Sequence Coverage, % Ratio of H/L, normalized
P04792 IPI00025512 Hsp27/HSPB1 2 12.7 2.0741
B4DR52 IPI00646240 Histone H2B 2 14.5 2.3519
Q13765 IPI00797126 Alpha-NAC 4 5.9 3.4854
  1. Abbreviations: Alpha-NAC Nascent polypeptide-associated complex subunit alpha, Hsp27 Heat shock protein 27, HSBP1 Heat shock protein beta-1, H/L ratio between proteins abundance in cells labeled with heavy isotopes compared to cells labeled with light isotopes, SILAC stable isotope labeling with amino acids in cell culture.