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Figure 6 | Molecular Cancer

Figure 6

From: Loss of miR-638 in vitro promotes cell invasion and a mesenchymal-like transition by influencing SOX2 expression in colorectal carcinoma cells

Figure 6

Knockdown of SOX2 inhibits the cell invasion and migration of CRC cell lines. (A) SOX2 was knocked down in CRC cells, and its protein expression was verified by Western blotting analysis. Invasion (B) and migration (C) were inhibited after SOX2 knockdown in HCT-116 and SW1116 cells (unpaired t-test). Matrigel-coated (for invasion) and -uncoated (for migration) transwell assays were performed after transfection with SOX2 siRNA for 48 hours.

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Molecular Cancer

ISSN: 1476-4598