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Figure 3 | Molecular Cancer

Figure 3

From: A novel approach to identify driver genes involved in androgen-independent prostate cancer

Figure 3

LV integrants are enriched in PCa susceptibility loci after selection for androgen-independence. Lentiviral integration sites (75) identified from LNCaP androgen-independent cultures in vitro or tumors from castrated animals (AI-LNCaP) were mapped relative to previously described PCa susceptibility loci (PCSL). The frequency of these sites was compared to LNCaP cells pre-selection (LNCaP) and to a control data set of 10,000 random sites. *indicates significant difference of p < 0.001.

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