Figure 1

miR-24 is significantly downregulated in GC and inhibited SGC-7901 cell growth. (A) Relative expression of miR-24 in nine GC cell lines compared with GES-1 determined by qRT-PCR of three independent experiments (**P < 0.01, ***P < 0.001). (B) Relative expression of miR-24 in surgical specimens of 63 GC determined by qRT-PCR. All experiments were performed in triplicate. Data are shown as -ΔΔCT values, S.D. not shown. (C) The mean and standard deviation of miR-24 expression levels in surgical specimens of 63 GC tissues and matched non-tumor tissues are shown. Data are presented as 2^-ΔCT values (**P < 0.05). U6 snRNA was used for normalization. (D) miR-24 inhibited the growth of SGC-7901 cells as detected by WST, while anti-miR-24 increased cell growth (*P < 0.05). Data are shown as mean ± S.D. of three independent experiments.