Figure 5
From: Tumor suppressor miR-24 restrains gastric cancer progression by downregulating RegIV
miR-24 inhibited tumorigenicity and proliferation in vivo. (A) Photograph of tumors derived from RV-miR-24 or RV-miR-control cells in nude mice. (B) Growth kinetics of tumors in nude mice. Tumor diameters were measured every 7 days. The volume of the nude mice indicated by bars, S.D. (*P < 0.05). (C) The average weight of tumors in nude mice. Data are shown as means ± S.D. (*P < 0.05). (D) Representative photographs of immunohistochemical analysis of Ki-67 antigen in tumors of nude mice (original magnification, 200×). (E) Representative proliferative index of tumors in RV-miR-24 and RV-miR-control nude mice. Data are shown as means ± S.D. (**P < 0.05). (F) Expression levels of RegIV in tumor tissues of nude mice. Data are shown as means ± S.D. (*P < 0.05). (G) Expression levels of RegIV mRNA in tumor tissues of nude mice (P > 0.05). Data are shown as mean ± S.D. of three independent experiments.