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Figure 1 | Molecular Cancer

Figure 1

From: Nutlin-3 overcomes arsenic trioxide resistance and tumor metastasis mediated by mutant p53 in Hepatocellular Carcinoma

Figure 1

Influence of arsenic trioxide or Nutlin-3 on HCC cell viability and apoptosis. All HCC cell lines were treated with arsenic trioxide or Nutlin-3 for 48 h and 72 h respectively. (A and B) The cell viability was determined using MTT assay. Data are presented as mean ± SD, ***: P < 0.001. (C) The apoptosis was examined using Annexin V-FITC Apoptosis Detection Kit. ***: P < 0.001 compared with the control. (D) The expression of MDM2, p53 and p-gp was investigated by Western blot in indicated cell lines.

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