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Table 2 Correlation between the expression of IGF-IR or Cbl-b and the clinicopathological factors in primary gastric cancer patients

From: Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells

Factors

All cases

IGF-IR

Cbl-b

  

Negative (%)

Positive (%)

P value

Negative (%)

Positive (%)

P value

Age a

       

 < 59

46

15 (32.6)

31 (67.4)

0.749

22 (47.8)

24 (52.2)

0.278

 ≥ 60

54

16 (29.6)

38 (70.4)

20 (37.0)

34 (63.0)

Gender

       

 Male

72

22 (30.6)

50 (69.4)

0.878

31 (43.1)

41 (56.9)

0.733

 Female

28

9 (32.1)

19 (67.9)

11 (39.2)

17 (60.8)

pTNM stage

       

 I + II

46

24 (52.2)

22 (47.8)

<0.001*

6 (13.0)

40 (87.0)

<0.001*

 III + IV

54

7 (13.0)

47 (87.0)

36 (66.7)

18 (33.3)

Lymph node metastasis

       

 Absent

50

26 (52.0)

24 (48.0)

<0.001*

6 (12.0)

44 (88.0)

<0.001*

 Present

50

5 (10.0)

45 (40.0)

36 (72.0)

14 (28.0)

Lauren grade

       

 Intestinal

22

8 (36.4)

14 (63.6)

0.614

7 (31.8)

15 (68.2)

0.452

 Diffuse

46

12 (26.1)

34 (73.9)

22 (47.8)

24 (52.2)

 mixed

32

11 (34.4)

21 (65.6)

13 (40.6)

19 (59.4)

  1. aMean age.
  2. *P <0.05.