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Table 2 Correlation between the expression of IGF-IR or Cbl-b and the clinicopathological factors in primary gastric cancer patients

From: Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells

Factors All cases IGF-IR Cbl-b
   Negative (%) Positive (%) P value Negative (%) Positive (%) P value
Age a        
 < 59 46 15 (32.6) 31 (67.4) 0.749 22 (47.8) 24 (52.2) 0.278
 ≥ 60 54 16 (29.6) 38 (70.4) 20 (37.0) 34 (63.0)
Gender        
 Male 72 22 (30.6) 50 (69.4) 0.878 31 (43.1) 41 (56.9) 0.733
 Female 28 9 (32.1) 19 (67.9) 11 (39.2) 17 (60.8)
pTNM stage        
 I + II 46 24 (52.2) 22 (47.8) <0.001* 6 (13.0) 40 (87.0) <0.001*
 III + IV 54 7 (13.0) 47 (87.0) 36 (66.7) 18 (33.3)
Lymph node metastasis        
 Absent 50 26 (52.0) 24 (48.0) <0.001* 6 (12.0) 44 (88.0) <0.001*
 Present 50 5 (10.0) 45 (40.0) 36 (72.0) 14 (28.0)
Lauren grade        
 Intestinal 22 8 (36.4) 14 (63.6) 0.614 7 (31.8) 15 (68.2) 0.452
 Diffuse 46 12 (26.1) 34 (73.9) 22 (47.8) 24 (52.2)
 mixed 32 11 (34.4) 21 (65.6) 13 (40.6) 19 (59.4)
  1. aMean age.
  2. *P <0.05.