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Table 2 Proportional hazards Cox regression models evaluating the association between miR-10b RERs and Overall Survival (OS), Disease Free Survival (DFS) and Metastases Free Survival (MFS) in the 90 cases without metastases at diagnosis

From: Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients

Outcome

Median follow-up (range)*

Events/Total

Model

HR

95% CI

p

Disease Free Survival (DFS)

39.88 (21.17 – 58.77)

34/90

Univariable

1.16

1.02-1.31

0.021

31/79

Multivariable

1.30

1.11-1.51

<0.001

Metastasis-Free Survival (MFS)

43.57 (25.23 – 59.77)

30/90

Univariable

1.17

1.03-1.34

0.019

27/79

Multivariable

1.34

1.13-1.59

<0.001

Overall Survival (OS)

45.78 (32.60 – 60.50)

18/90

Univariable

1.20

1.04-1.38

0.015

  

16/79

Multivariable

1.31

1.10-1.57

0.003

  1. Abbreviations: HR Hazard Ratio, 95% CI, 95% Confidence Interval.
  2. Multivariable models included: T, N, Grade, ER, PgR, HER2 and KI67.
  3. HR were reported for each unitary increase of 0.1 miR-10b RERs.