Figure 4From: Inhibition of the checkpoint kinase Chk1 induces DNA damage and cell death in human Leukemia and Lymphoma cellsInhibition of Chk1 by V158411 prevents entry into mitosis. Jurkat, Raji or U937 cells were treated with 1 μM V158411 in the presence or absence of 0.1 μM nocodazole for 24 hours. Changes to protein markers were evaluated by western blotting.Back to article page