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Figure 2 | Molecular Cancer

Figure 2

From: CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis

Figure 2

CD133 acts as a regulator of the mesenchymal phenotype. (A) A heatmap of the DNA microarray demonstrates the distinct molecular profiles of Capan1M9 and shCD133M9 cells. (B) A heatmap of EMT-related genes with a Z-score greater than 2 distinguished between Capan1M9 and shCD133M9 cells. (C) Validation of the levels of the EMT-related proteins fibronectin, N-cadherin, and E-cadherin in Capan1M9 and shCD133M9 cells by Western blot. (D) Validation of EMT-related genes in Capan1M9 with shCD133M9 cells by real-time RT-PCR.

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Molecular Cancer

ISSN: 1476-4598