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Figure 1 | Molecular Cancer

Figure 1

From: Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes

Figure 1

Acquisition of the PSNE gene signature. (A) NHEK growth curve and representative photomicrographs of senescent (S) and emergent NHEKs (E) as compared to NHEKs in exponential growth phase (Y) observed by phase-contrast microscopy. (B) Number of differentially up- and down-regulated genes in E versus Y NHEKs and E versus S NHEKs analysed with a range of FDR filters from 1 to 0.1%. (C) Venn diagram showing the PSNE gene signature defined by the overlap of differentially expressed genes in E vs Y and E vs S NHEKs.

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Molecular Cancer

ISSN: 1476-4598