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Figure 2 | Molecular Cancer

Figure 2

From: Higher FOXP3-TSDR demethylation rates in adjacent normal tissues in patients with colon cancer were associated with worse survival

Figure 2

CRC cell lines express very low levels of demethylated FOXP3- TSDR and FOXP3 mRNA. HEK 293T cells, which do not express FOXP3 mRNA, served as negative controls. (A) Compared to nTregs, CRC cell lines showed lower levels of demethylated FOXP3-TSDR based on an MS-qPCR assay. (B) Extremely low levels of FOXP3 mRNA expression were observed among CRC cell lines when compared to nTregs based on a real-time RT-PCR assay.

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Molecular Cancer

ISSN: 1476-4598