Figure 2
From: Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration
Time-lapse microscopy reveals an inhibition of the motility of MDA-MB-436 cells upon salinomycin treatment. A) Wound healing assay of MDA-MB-436 cells. Cells were treated either with mock (control), doxorubicin (0.05 μM) or salinomycin (0.05 μM) and monitored for 72 h. The same cells as for the wound healing assay were used for time-lapse microscopy. Manually tracked cells were analyzed for B) the accumulated distance, C) the velocity and D) the direction of movement. (Student’s t-test, two-tailed, ****p < 0.0001).