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Figure 2 | Molecular Cancer

Figure 2

From: Thyroid hormone enhanced human hepatoma cell motility involves brain-specific serine protease 4 activation via ERK signaling

Figure 2

BSSP4 promotes cell motility in vitro. Expression of BSSP4 was detected in BSSP4-overexpressing clones (#1, #2) and controls (control #1, #2) with Western blotting (A). (B) Migration and (C) invasion abilities were analyzed in two BSSP4 overexpressing and two control cell lines using a Transwell assay. The number of cells traversing the filter to the lower chamber was expressed as the total number of cells to provide an index of migration and invasion activity. Transwell filters were stained with crystal violet in the left panel, and migration and invasion abilities quantified in the right panel. (D) Expression of BSSP4 in Mahlavu-control cells (#1, #2) and Mahlavu-BSSP4-KD cells (#1, #2) was determined by Western blotting. The migration ability was also examined with a Transwell assay (E).

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