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Figure 1 | Molecular Cancer

Figure 1

From: miRNA-200c inhibits invasion and metastasis of human non-small cell lung cancer by directly targeting ubiquitin specific peptidase 25

Figure 1

Correlation analysis of miR-200c expression and invasion capacity. (A) Levels of miR-200c expression in 7 human NSCLC cell lines were measured by quantitative real-time RT-PCR. U6 was used for normalization. (B and C) The invasion and migration ability of 7 human NSCLC lines was determined by using the matrigel migration and invasion assay. (D-G) Transwell migration and invasion assays for SPC-A-1sci, H1299, and A549 cells were performed after transduction with by miR-200c mimics or miR-controls, and SPC-A-1 cells were performed after transduction with miR-200c inhibitor or miR-control. The results are representative of at least three independent experiments. Statistical analysis was performed using Student’s t- test. Error bars represent S.E.M. *P < 0.05; **P < 0.01; ***P < 0.001.

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Molecular Cancer

ISSN: 1476-4598