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Figure 2 | Molecular Cancer

Figure 2

From: Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis

Figure 2

Claudin-1 overexpression promotes inflammation driven colon tumorigenesis. (A) Endoscopic images were obtained from APCMin and APC-Cldn1 mice under conditions of regular drinking water (control) (n = 3) and 2% DSS w/v in drinking water (treated) (n = 5) mice at the indicated time points, following 7 days of DSS administration. (B) Tumor number/mice in DSS-treated APCMin versus APC-Cldn1 mice (p = 0.022) (C) Representative H&E images. Values are mean ± S.E.M. *p < 0.05.

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Molecular Cancer

ISSN: 1476-4598