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Figure 1 | Molecular Cancer

Figure 1

From: Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner

Figure 1

Nicotine and EGF induces expression of STMN3 and GSPT1 in NSCLC cell lines; and depletion of ID1 by siRNA reduced this induction. (A & B) RT-PCR showing significant fold reduction in STMN3 and GSPT1 in A549. (C & D) Similar results were obtained in H1650 cells, (E) Western blot analysis showing the upregulation of STMN3 & GSPT1 proteins by nicotine and EGF in non-targeting control siRNA cells and absence of induction in ID1 depleted A549 cells, (F) similar results were obtained in H1650 cells. The above data are expressed as mean ± SD of three independent experiments. *represents p value of <0.05; **represents p value of <0.02.

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Molecular Cancer

ISSN: 1476-4598