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Figure 1 | Molecular Cancer

Figure 1

From: Influence of secreted frizzled receptor protein 1 (SFRP1) on neoadjuvant chemotherapy in triple negative breast cancer does not rely on WNT signaling

Figure 1

Expression of SFRP1 correlates with the triple negative breast cancer subtype. A) SFRP1 was found to be upregulated in TNBC compared to non-TNBC; shown here are all three probesets 202035_s_at, 202036_s_at and 202037_s_at (TN = triple negative). B) Expression of SFRP1 in breast cancer tissue specimens of 362 patients (TNBC = 37patients); scores 0 (negative), 1 (weak positive), 2 (positive), 3 (strong positive). C) Boxplot analysis of immunohistochemical staining. D) Protein and mRNA levels of SFRP1 in different breast (cancer) cell lines (non-tumorigenic epithelial cell line: MCF-10A, TNBC cell lines: HCC1937, MDA-MB-468, BT-20, MDA-MB-453, HCC 1806 and MDA-MB-231; non-TNBC cell lines SKBR-3 and MCF-7) (n.d. = not detected).

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Molecular Cancer

ISSN: 1476-4598