Skip to main content
Figure 3 | Molecular Cancer

Figure 3

From: Influence of secreted frizzled receptor protein 1 (SFRP1) on neoadjuvant chemotherapy in triple negative breast cancer does not rely on WNT signaling

Figure 3

Downregulation of SFRP1 changes carcinogenic properties of triple negative breast cancer cells. A) Representative pictures of migration and invasion filters after SFRP1 knockdown in MDA-MB-468 cells. B) Quantitative analysis of migration and invasion assays after SFRP1 knockdown revealed increase in migration of about 15% and increase in invasion potential of about 30% ((*p < 0.05), error bars = SD, n = 3) C/D) Flow cytometry analysis using Annexin V staining showed a slight decrease of cells undergoing apoptotic (C: Q4) as well as late apoptotic or necrotic events (C: Q1 and Q2).

Back to article page

Molecular Cancer

ISSN: 1476-4598