Figure 1
From: KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer
KIF5B-RET fusion gene is identified in a Chinese LAD patient. A. Expression of the KIF5B-RET fusion protein is shown in the positive tumor sample. Western blot analysis showed an approximately 108Â kDa but not 170Â kDa (the RET protein) band. B. Immunohistochemical analysis of KIF5B-RET expression in the positive tumor tissue. The tumor cells were arranged in solid nests and revealed moderate cytoplasmic expression of KIF5B-RET fusion protein.