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Figure 3 | Molecular Cancer

Figure 3

From: Effective inhibition of melanoma tumorigenesis and growth via a new complex vaccine based on NY-ESO-1-alum-polysaccharide-HH2

Figure 3

NAPH increases NY-ESO-1-specific antibody immune response. A, The titers of anti-NY-ESO-1 total IgG were measured using ELISA. Dot, titer of each mouse. B, C, The titers of anti-NY-ESO-1 IgG2a/IgG1 titers in the treated groups were measured. D, FACS analysis using NY-ESO-1-B16 cells to detect NY-ESO-1-specific IgG antibodies (n = 3 mice, pooled composite results are shown). E, Antibody-dependent cellular cytotoxicity was determined using the 51Cr-release assay. NY-ESO-1-B16 cells were labeled with 51Cr and coated with sera from control or treated mice. Splenocytes from untreated or treated mice were used as effectors. The assay was run in three replicates.

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