Figure 2
From: TCAB1: a potential target for diagnosis and therapy of head and neck carcinomas
Depletion of TCAB1 reduced the cell proliferation in vitro . a. qPCR results. Using exogenous shTCAB1 lentivirus (4 different shRNA targets) depleted TCAB1 mRNA significantly. b. Protein level also significantly decreased after shTCAB1 lentivirus treatment. c. Depletion of TCAB1 by exogenous shRNA decreased cell proliferation in Cal-27, ACC2 and HSC-3 cells. d. FACS results. Depletion of TCAB1 might facilitate cancer cell arrest, and shTCAB1-treated cells are significantly less in S phase. Statistical analysis was determined by Student’s t test (**P < 0.01, ***P < 0.005).