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Figure 1 | Molecular Cancer

Figure 1

From: ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex

Figure 1

ISL-1 is highly expressed in the majority subtypes of NHL. (A) Immunohistochemistry for ISL-1 expression in normal lymph nodes and multiple subtypes of lymphoma specimens was performed. Representative images of ISL-1 expression level and cellular distribution in different samples are shown (200 ×). Scale bars = 100 μm. (B) Staining scores of ISL-1 in normal lymph nodes, HL and NHL were statistically analyzed by χ2 test. (C to D) The mRNA and protein levels of ISL-1 in NHL cell lines and health human peripheral white blood cells (PBC) were analyzed by RT-PCR (C) and Western blot (D) analysis. Numbers 1–7 represent PBC samples from different donors.

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Molecular Cancer

ISSN: 1476-4598