Figure 2

ISL-1 promotes NHL cells proliferation and affects cell-cycle phase distributions. (A) The relative proliferation rate of stably transfected cells was determined by CCK-8 assay at indicated time post-seeding. (B) Cell cycle distributions were analyzed by flow cytometry. The data represent three independent experiments. Each bar represents mean ± SD. p values were calculated using a Student t-test (*p < 0.05, **p < 0.01, ^#p < 0.05, ^##p < 0.01 vs. each control). (Control, ISL-1, Non-silencer and ISL-1 siRNA represent the cells transfected with pcDNA3.1, pcDNA3.1-ISL-1, pLL3.7-Non-silencer or pLL3.7-ISL1-siRNA plasmid, respectively)