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Figure 1 | Molecular Cancer

Figure 1

From: miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis

Figure 1

Consistent down-regulation of miR-31 in NPC. By quantitative RT-PCR, loss or high reduction of miR-31 expression was detected in (a) a NPC cell line, 5/6 xenografts and (b) all 37 primary tumors. The immortalized normal nasopharyngeal epithelial cell line NP69 and microdissected normal epithelia (Normal 1–3) were included as controls. (c) Representative images of in-situ hybridization showing the high miR-31 expression in normal nasopharyngeal epithelia and loss of miR-31 expression in the NPC tumor cells (red arrow) (X400). (d) By in situ hybridization, loss of miR-31 expression was found in 2/4 dysplastic lesions (black arrow) (X400).

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Molecular Cancer

ISSN: 1476-4598