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Table 1 Clinicopathological features of the lung cancer family with PROM1 and CRTC2 mutations

From: Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients

Patient ID Gender Age (years) Alcohol consumption Tobacco smoking Pack years Medical history Histological type TNM (Stage) Tumor differentiation PROM1 mutation CRTC2 mutation
           Nucleotide change Amino acid change Nucleotide change Amino acid change
II4 Male 65 Frequent Former 1095 COPD, bronchiectasis Adenocarcinoma T1aN0M0 Moderate 841 T > G S281R 1135G > A R379C
III1 Male 51 Frequent Former 365 None Adenocarcinoma T1bN0M0 Poor-moderate 841 T > G S281R 1135G > A R379C
III4 Female 37 Never Never   None N/A N/A N/A None None None None
IV1 Male 10 Never Never   None N/A N/A N/A None None None None